• 1683: Robert Delaunay
• 1783: Jean-Baptiste Micot
• 1983: Restauration Gerhard Grenzing

The organ of Saint-Pierre des Chartreux was originally built for the church of the Jacobins convent by Robert Delaunay (or de Launay) after a contract concluded with the Friars Preachers on 13 March 1677. It was completed on 12 January 1683 and appraised by Jean de Joyeuse on the following 6 September. Its composition, similar to that of the organ he built for the Basilica of Saint-Sernin three years earlier, was as follows Positif (48 notes, C1 - C5 without C#1): Bd 8', P 4', Fl 4', Nz 2' 2/3, D 2', Tc 1' 3/5, Flajoulet 1', Fourn III, Cymb III, Petit Cornet III, Cr 8', Cr 4' Grand-Orgue (48 notes, C1 - C5 without C#1) : Bd 16', M 8', Bd 8', P 4', Fl 4', Nz 2' 2/3, D 2', QdNz 2', Tc 1' 3/5, Lg 1' 1/3, Tierselette II, GFourn II, PFourn III, Cymb IV, Cn V, Tp 8', VH 8', Cl 4' Echo (37 notes, C2 - C5): Bd 8', P 4', Nz 2' 2/3, D 2', Tc 1' 3/5, Cymb III, Cr 8' Pedalboard (18 notes) : Fl 8', Fl 4', Tp 8' Rossignol, Tremblant à vent perdu. Between 1750 and 1760, the organ was increased by a trumpet and a flute 8' in the Great Organ and in the Positif, a Clairon and a revival in F for the Pedal reeds, the pipework was shifted and the organ was lowered by a semitone. This work was carried out by Jean-Esprit Isnard and Joseph Cavaillé who had their workshop in the convent. Under a contract dated 18 December 1783, the organ was restored by Jean-Baptiste Micot, who, in addition to refurbishing the blower and keyboards, restoring the entire mechanism and pipework and completely overhauling the harmony, replaced the Echo manual with a Recital manual starting at G2 and including a Prestant without register, a Cornet and a Trumpet. This work was completed on 10 October 1784. It was the same Micot who transported the instrument to the new church of Saint-Pierre des Chartreux after having "increased it... with a new full stop made of Cornish pewter with fourteen pipes per key" (report of 26 prairial year 4 in which he judged the organ to be "one of the most complete in this region with the most perfect harmony. In 1850, the organ was restored and brought up to date by Frédéric Jungk with the consent of the organist of Saint-Pierre, also an organ builder, Auguste Montlezun. Eugène Puget took over the organ in 1880/81, then in 1899, Jean-Baptiste Puget restored the instrument and transformed the positive (change of stops, reharmonization, addition of a new Principal 8' of 42 notes, reed call...). In 1958, Maurice Puget made an attempt to return to the old organ and his work was inaugurated on 21 November of that year by Xavier Darasse, "Laureate of the Conservatoire National Supérieur de Musique de Paris, with a programme including works by Bach, Clérambault, Dupré, Messiaën. The organ was finally restored by Gerhard Grenzing in a programme aimed at recovering the original 17th century harmony. This work was inaugurated by Gaston Litaize on 29 October 1983. The instrumental part of the Great Organ was classified as a historical monument on 6 October 1969.